Track record · closed signal

Stoke Therapeutics, Inc. (STOK) — closed signal from December 15, 2025

Partial Published before the outcome was known, scored automatically when the window closed on March 15, 2026.

Predicted vs. what happened

STOK price · publication thesis → realized outcomesplit-adjusted
$34.14 Published $49.50 Target $33.19 Window close $40.22 Peak
$33.00 – $35.00Entry zone — fair-value band
$34.14Published — price the day we called it
$49.50Target — the price the thesis aimed for
$40.22Peak — highest point inside the window, not a realized return
$33.19Window close — end-of-window price, context only

What happened

Partial

Reached 40% of the predicted growth at its peak, without hitting the target.

Peak price
$40.22
peak on March 10, 2026 — not a realized return
Peak gain
+17.8%
peak, from the publication price
Window close
$33.19
end-of-window price, context only
Days to target
Window
December 15, 2025 – March 15, 2026

The thesis — published December 15, 2025

Predicted growth
+45%
over the measurement window
Target price
$49.50
the price the thesis aimed for
Entry zone
$33.00 – $35.00
the fair-value band we waited for
Price at publication
$34.14
published December 15, 2025
Confidence
95%
how strongly the data lined up
Timeframe
Short-term (0–3 months)

This biotech stock often moves a lot. Recent clinical news about its Dravet program with Biogen caused a strong after-hours jump and heavy trading, suggesting more people are buying than usual. Some insiders sold options, which raises risk. The setup looks like a short-term rebound opportunity, but use small entries and tight risk limits.

Primary drivers

  • Good long-term Dravet trial results with Biogen could change investor views
  • Big after-hours jump and heavy trading suggest rising buyer interest
  • Indicator showed oversold then flipped bullish, pointing to a short-term rebound
  • Biotech stocks move strongly around news, which can magnify gains or losses

How it played out

STOK: thesis rose but target was not reached

Lyra published STOK on 2025-12-15 at $34.14 with an expected growth of 45%. The thesis pointed to Dravet trial results with Biogen, a big after-hours jump with heavy trading, an oversold indicator that had flipped bullish, and the way biotech stocks could move strongly around news. It also noted insider option sales as a risk.

Inside the window, STOK peaked at $40.22 on 2026-03-10. That was a 17.8% gain, but it stayed below the $49.50 target. The target was never reached. The window ended at $33.19. The thesis partially played out because the stock rose, but the published upside did not arrive.

Prices are shown split- and dividend-adjusted, matching what public charts show today.

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This is one signal, scored after the fact. Today’s picks come with the same plain-language thesis — published before anyone knows the outcome.